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Ascentage Pharma Group Internat AAPG PHARMA

Healthcare · Biotechnology · China
https://www.ascentage.cn
Company Profile ↓
$17.44
-57.62% 1Y
Mkt Cap$1.63B
P/E-7.39
P/B16.94
52W High$47.90
52W Low$16.23
Book Value$0.89
EPS (TTM)$-2.36

Company Overview

Ascentage Pharma Group International, a clinical-stage biotechnology company, develops therapies for cancers, chronic hepatitis B virus (HBV), and age-related diseases in Mainland China. The company's primary product candidate is HQP1351, a BCR-ABL inhibitor targeting BCR-ABL1 mutants, including those with the T315I mutation. It also develops APG-2575, an oral administered Bcl-2 selective inhibitor for hematologic malignancies and solid tumors; APG-115, an oral small molecule inhibitor of the MDM2-p53 protein-protein interactions to treat solid tumors and hematological malignancies; and APG-1252, a small molecule drug to restore apoptosis through dual inhibition of the Bcl-2 and Bcl-xL proteins for the treatment of small-cell lung cancer, non-small cell lung cancer, neuroendocrine tumor, and non-Hodgkin's lymphoma. In addition, the company is developing APG-1387, a small-molecule inhibitor of apoptosis proteins for advanced solid tumors and chronic HBV infection; APG-5918, an orally available and selective embryonic ectoderm development inhibitor. In addition, it is involved in medical research and development; clinical development; clinical trials operations; venture capital investment; rental of buildings; and provision of science and technology promotion services. The company has strategic partnership with biotechnology and pharmaceutical companies; research institutions; and Peking University to build a collaborative system for hematological oncology. Ascentage Pharma Group International was founded in 2009 and is headquartered in Suzhou, China.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 39.9% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $574.12M (-41.5% YoY); net profit $-1.24B.
  • Trailing 12 Months Year-on-year growth — revenue +29.3%.
  • 5-Year Trend Long-term compounding — revenue CAGR 39.9%, profit CAGR -13.6%.

Growth & Price Performance

Compounded Sales Growth

5 Years:39.89%
1 Year:29.30%

Compounded Profit Growth

5 Years:-13.59%
1 Year:-

Stock Price Performance

1 Year:-57.62%
6 Months:-26.38%
3 Months:+1.87%
1 Month:-8.14%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 4% of range
$16.23 $47.90
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)47.95 · Neutral
Price Performance
1M-8.14%
3M+1.87%
6M-26.38%
1Y-57.62%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 39.9% over 5 years.

CONS

  • Earnings shrank at -13.6% CAGR over 5 years.
  • Trading 63.6% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-7.39
Industry PE
24.83
Forward P/E
-16.82
PEG Ratio
-
Book Value
$0.89
Price to Book
16.94
P/S
2.19
EV/EBITDA
-1.21
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
39.89%
Profit 5Y
-13.59%
Revenue (YoY)
29.30%
Earnings (YoY)
-

Profitability & Returns

ROCE
-50.94%
ROE
-
ROA
-28.04%
Profit Margin
-
Op Margin
-
Gross Margin
93.93%
EPS (Latest Qtr)
$-
EPS (TTM)
$-2.36

Balance Sheet & Liquidity

Debt/Equity
3.70
Quick Ratio
1.09
Current Ratio
1.22
Debt
$2.09B
Total Assets
$3.24B
Current Assets
$2.29B
Working Capital
$1.30B

Ownership

Promoter Holding
0.00%
Chg in Prom Hold
-
FII / Inst Holding
0.04%
Chg in FII Hold
0.00%

Financial Snapshot

Enterprise Value
$1.63B
Total Revenue (TTM)
$642.64M
EBITDA
$-1.34B
Free Cash Flow
$-956.54M
Operating Cash Flow
$-1.32B
Shares Outstanding
93.39M
Gross Margin
93.93%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 AAPG Ascentage Pharma Group Internat PHARMA 17.44 -7.39 $1.63B 0.00% -50.94% - 39.89% -13.59%
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -209.71M221.98M980.65M574.12M
Cost of Revenue -22.00M30.54M29.09M48.94M
Gross Profit -187.71M191.44M951.57M525.18M
Operating Expenses -1.04B1.06B1.32B1.72B
Operating Income --849.81M-872.64M-369.73M-1.20B
EBITDA --771.47M-743.61M-237.63M-1.10B
Interest Expense -52.78M96.06M64.45M54.07M
Pretax Income --887.17M-932.86M-395.25M-1.24B
Tax Provision --4.25M-7.15M10.43M6.94M
Net Income --882.92M-925.64M-405.43M-1.24B
Diluted EPS --13.40-13.12-5.36-13.96

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -2.83B2.50B2.62B3.96B
Current Assets -1.64B1.34B1.47B2.94B
Cash & Equivalents -1.48B1.07B1.24B2.46B
Inventory -9.45M16.17M6.60M28.62M
Receivables -54.36M145.89M83.14M252.94M
Total Liabilities -2.42B2.43B2.34B2.63B
Current Liabilities -881.15M934.17M1.17B1.64B
Long Term Debt -1.27B1.17B868.64M742.33M
Total Debt -1.79B1.80B1.67B1.98B
Total Equity -408.66M60.42M264.19M1.32B
Shares Outstanding -265.19M290.20M315.22M373.32M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow --653.91M-726.08M-111.36M-1.17B
Investing Cash Flow --384.61M21.92M-362.04M-1.00B
Financing Cash Flow -619.27M368.75M314.77M2.54B
Capital Expenditure --236.96M-56.84M-24.29M-27.57M
Free Cash Flow --890.88M-782.92M-135.65M-1.20B
Net Change in Cash --419.26M-335.40M-158.62M365.92M

Ratios (Annual)

Figures in %.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -89.5%86.2%97.0%91.5%
Operating Margin % --405.2%-393.1%-37.7%-208.6%
Net Margin % --421.0%-417.0%-41.3%-216.5%
ROE % --216.1%-1,532.1%-153.5%-93.8%
ROCE % --43.6%-55.7%-25.5%-51.6%

Shareholding Pattern

Insiders
0.00%
Institutions
0.04%
Public Float
0.04%

Top Institutional Holders

#Holder% HeldSharesValue
1 Point72 Asset Management, L.P. 0.01% 13.84K $208.44K
2 Eversource Wealth Advisors, Llc - 24 $361
3 Caitong International Asset Management Co., Ltd - 1 $15
4 Blackrock Inc. - 6 $90
5 Morgan Stanley - 919 $13.84K
6 UBS Group AG - 15 $225
7 Wells Fargo & Company - 200 $3.01K
8 Royal Bank of Canada - 6 $90

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for AAPG

Yahoo Finance Wed, 02 Sep 2026

Ascentage Pharma to Participate in Four Upcoming Investor Conferences

ROCKVILLE, Md., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855) (“Ascentage Pharma” or the “Company”), a global, commercial-stage, integrated biopharmaceutical company engaged in the discov…

Yahoo Finance Fri, 21 Aug 2026

ASCENTAGE PHARMA GROUP INTERNATIONAL Q2 2026 Earnings Call Summary

Moby summary of ASCENTAGE PHARMA GROUP INTERNATIONAL's Q2 2026 earnings call

Yahoo Finance hu, 20 Aug 2026

Ascentage Pharma Group International H1 Earnings Call Highlights

Ascentage Pharma Group International (NASDAQ:AAPG) reported first-half 2026 revenue growth as it continued investing in global registrational studies for its hematology-oncology pipeline and began building commercial capabilities outside Ch…

Yahoo Finance Wed, 19 Aug 2026

Ascentage Pharma Reports 2026 Interim Unaudited Financial Results and Provides Business Updates

Revenue for the first half of 2026 increased 29% year-over-year to US$44.5 million (RMB302.2 million), primarily attributable to increased product sales. Expanded executive leadership with appointments of Dr. Faical Miyara as Chief Business…

Yahoo Finance Fri, 28 Aug 2026

Ascentage Pharma Group International (SEHK:6855) Could Be 18% Undervalued After Half Year Losses

Half year earnings put Ascentage Pharma Group International (SEHK:6855) losses in focus Ascentage Pharma Group International (SEHK:6855) released half year earnings to June 30, 2026, reporting sales of CNY 302.21 million and a net loss of C…

Yahoo Finance hu, 13 Aug 2026

Ascentage Pharma to Participate in the Evercore 2nd Annual China Biotech Summit

ROCKVILLE, Md., Aug. 13, 2026 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855) (“Ascentage Pharma” or the “Company”), a global, commercial-stage, integrated biopharmaceutical company engaged in the discove…

AAPG — Frequently Asked Questions

What is the current share price of Ascentage Pharma Group Internat (AAPG)?

As of 2026-09-19 21:16 PDT, Ascentage Pharma Group Internat (AAPG) trades at $17.44 on NasdaqGM. Its 52-week range is $16.23 to $47.90.

What is the market capitalisation of AAPG?

Ascentage Pharma Group Internat (AAPG) has a market capitalisation of $1.63B on NasdaqGM.

What is the P/E ratio of AAPG?

AAPG trades at a trailing price-to-earnings (P/E) ratio of -7.39. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 16.94.

Is AAPG a good stock to buy?

This page provides a data-driven analysis of Ascentage Pharma Group Internat (AAPG), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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